Dr Fragen in the operating room

TPA and the Trauma Patient


In case you didn’t know or were wondering, using [TPA][] in the trauma patient isn’t a good idea. It’s especially bad when the path of the bullet went across to top of the liver. And before you ask, yes there was a vascular injury and yes a vascular surgeon used the TPA.
I guess another way to say it is, “Why you should open the patient’s abdomen 3 different times before they leave the OR.”
Bottom line: [Factor VII][1] is great stuff and we closed the abdomen for the final time about 36 hours later.
[tpa]: http://en.wikipedia.org/wiki/Tissue_plasminogen_activator
[1]: http://en.wikipedia.org/wiki/Factor_vii